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NIP45 controls the magnitude of the type 2 T helper cell response.
Fathman JW, Gurish MF, Hemmers S, Bonham K, Friend DS, Grusby MJ, Glimcher LH, Mowen KA. Fathman JW, et al. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3663-8. doi: 10.1073/pnas.0914700107. Epub 2010 Feb 4. Proc Natl Acad Sci U S A. 2010. PMID: 20133688 Free PMC article.
Nuclear factor of activated T cell (NFAT) transcription factors are key regulators of gene transcription within immune cells. ...Whereas NIP45 deficiency does not interfere with T helper cell NFAT activation or lineage-specific transcription- …
Nuclear factor of activated T cell (NFAT) transcription factors are key regulators of gene transcription within …
Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).
Lieberson R, Mowen KA, McBride KD, Leautaud V, Zhang X, Suh WK, Wu L, Glimcher LH. Lieberson R, et al. J Exp Med. 2001 Jul 2;194(1):89-98. doi: 10.1084/jem.194.1.89. J Exp Med. 2001. PMID: 11435475 Free PMC article.
Recently we have identified a novel protein NIP45 (nuclear factor of activated T cells [NFAT]-interacting protein) which substantially augments interleukin (IL)-4 gene transcription. ...We present evidence that members of th …
Recently we have identified a novel protein NIP45 (nuclear factor of activated T cells [NFAT]-i …
Establishment of a human cell line stably overexpressing mouse Nip45 and characterization of Nip45 subcellular localization.
Hashiguchi K, Ozaki M, Kuraoka I, Saitoh H. Hashiguchi K, et al. Biochem Biophys Res Commun. 2013 Jan 4;430(1):72-7. doi: 10.1016/j.bbrc.2012.11.020. Epub 2012 Nov 15. Biochem Biophys Res Commun. 2013. PMID: 23159618
The nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein, Nfatc2ip (Nip45), has been implicated as a crucial coordinator of the immune response and of cellular differentiation …
The nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting …
Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes.
Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH. Mowen KA, et al. Mol Cell. 2004 Aug 27;15(4):559-71. doi: 10.1016/j.molcel.2004.06.042. Mol Cell. 2004. PMID: 15327772 Free article.
Posttranslational modification of proteins within T cell receptor signaling cascades allows T lymphocytes to rapidly initiate an appropriate immune response. ...Inhibition of arginine methylation impaired the expression of several cytokine genes, including th …
Posttranslational modification of proteins within T cell receptor signaling cascades allows T lymphocytes to rapidly in …